Department of Biopolymers Chemistry

dr hab. Marcin K. Chmielewski

Dr. habil. Marcin K. Chmielewski

Head of Department

chmielewskimk@ibch.poznan.pl
ext.​ ​1257

Researchers:

Dr. ​Stanisław Trzciński
adiunkt

Research Projects

Research area
  • research in chemical synthesis of biopolymers such as nucleic acids, peptides, carbohydrates and lipids.
  • application of original thermocyclization reaction in wider aspect of chemical synthesis.
  • Thermolability as tools in design of protecting groups, fluorescent labels, thermo-dependent catalysts and in polymerization reactions.
  • investigate in chemistry of examined compounds, to define the mechanism of observed processes and to obtain useful materials applicable in area of Life Sciences.
  • instrumental analysis using PVA capillary electrophoresis, High Pressure Liquid Chromatography (HPLC) with UV-Vis, fluorescence and korona detectors.
Keywords
  • protecting groups,
  • thermolabile protecting groups,
  • nucleic acids synthesis,
  • DNA, RNA, modifications,
  • thermosensitivity,
  • thermolability,
  • cross-linking,
  • fluorescent labels,
  • fluorescent dyes,
  • fluorescence,
  • infra-red,
  • FRET,
  • quencher,
  • polymers,
  • biopolymers,
  • aptamers,
  • functional groups,
  • nanostructures,
  • nanomachines,
  • nanodevices,
  • catalysis,
  • solid-phase,
  • markers,
  • larg-scale synthesis,
  • polystyren,
  • HPLC,
  • capillary electrophoresis,
  • PVA

Research activity

  • High-efficiency resins for solid-phase synthesis of biomolecules. NCRD – PBS1
  • Development of method of chemical synthesis of bio-active triphosphates using thermolabile protecting. NSC – OPUS 4
  • Synthesis and characterization of novel functional organic silicon compounds as silica functionalising agent. NSC – OPUS 5
  • Thermolytic fluorescent dyes in nucleic acid labelling. co-funded by the European POIR.01.01.01-00-0027/17-00. 01.10.2017 – 30.09.2020 head of the project
  • “Regulated Assembly of Molecular Machines for DNA Repair: a Molecular Analysis Network” (DNARepairMan) as part of Innovative Training network supported through EU Horizon 2020 Marie Sklodowska-Curie Action under project number H2020-MSCA-ITN-2016 [DNAREPAIRMAN - 722433]. 31.01.2017-30.01.2020 project executive
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