Department of Functional Transcriptomics

dr hab. Kamilla Grzywacz

Dr. habil. Kamilla Grzywacz

Head of Department
Phone: 61 8291866

Technical Staff:

Kamila Pepłowska MSc. BEng.

Weronika Pawlik MSc

Research Projects

Research area

The research profile of the Functional Transcriptomics Team includes the identification and characterization of molecular mechanisms of RNA-based gene expression regulation in model pro- and eukaryotic organisms, as a response to environmental changes.

Our research interest includes the following topics:

  • identification, characterization and determination of the regulatory potential of small ribosome-associated noncoding RNAs (rancRNA) in Saccharomyces cerevisiae under various environmental conditions, with particular emphasis on heterogeneity of ribosomes,
  • identification of riboswitches which regulate transcription and translation in model bacterium Bacillus subtilis,
  • comprehensive characterization of changes in the transcriptional, translational and regulatory activity induced in response to antibiotic stress and culture in infectious conditions in the drug-resistant strain Staphylococcus aureus, with special emphasis on the therapeutic potential of regulatory RNAs.
Słowa kluczowe
  • regulatorowe RNA,
  • niekodujące RNA,
  • krótkie RNA oddziałujące z rybosomem (rancRNA),
  • ryboprzełączniki.

Research activity

  • Changes in the ribosomal protein composition and in the ribosome-associated small noncoding RNAs in Saccharomyces cerevisiae as a response to environmental stress NCN – Opus 14
  • Designing a new method for direct identification and absolute quantification of premature transcription termination events, following the example of bacterial riboswitches NCN – Preludium 12
  • RNA regulatory networks as novel antimicrobial targets in multidrugs resistant bacteria (cooperation with Department of Computational Biology, Biology Faculty UAM in Poznań). NCN – Opus 13
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