Department of Functional Transcriptomics

dr hab. Kamilla Grzywacz

Dr. habil. Kamilla Grzywacz

Head of Department

kamilla.grzywacz@ibch.poznan.pl
Phone: 61 8291866

Technical Staff:

Kamila Pepłowska MSc. BEng.
biologist

Weronika Pawlik MSc
biologist

Research Projects

Research area

The research profile of the Functional Transcriptomics Team includes the identification and characterization of molecular mechanisms of RNA-based gene expression regulation in model pro- and eukaryotic organisms, as a response to environmental changes.

Our research interest includes the following topics:

  • identification, characterization and determination of the regulatory potential of small ribosome-associated noncoding RNAs (rancRNA) in Saccharomyces cerevisiae under various environmental conditions, with particular emphasis on heterogeneity of ribosomes,
  • identification of riboswitches which regulate transcription and translation in model bacterium Bacillus subtilis,
  • comprehensive characterization of changes in the transcriptional, translational and regulatory activity induced in response to antibiotic stress and culture in infectious conditions in the drug-resistant strain Staphylococcus aureus, with special emphasis on the therapeutic potential of regulatory RNAs.
Słowa kluczowe
  • regulatorowe RNA,
  • niekodujące RNA,
  • krótkie RNA oddziałujące z rybosomem (rancRNA),
  • ryboprzełączniki.

Research activity

  • Changes in the ribosomal protein composition and in the ribosome-associated small noncoding RNAs in Saccharomyces cerevisiae as a response to environmental stress NCN – Opus 14
  • Designing a new method for direct identification and absolute quantification of premature transcription termination events, following the example of bacterial riboswitches NCN – Preludium 12
  • RNA regulatory networks as novel antimicrobial targets in multidrugs resistant bacteria (cooperation with Department of Computational Biology, Biology Faculty UAM in Poznań). NCN – Opus 13
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