Department of Molecular Virology

dr Paweł Zmora

Dr. Paweł Zmora

Head of Department

pzmora@ibch.poznan.pl
ext. 1142

Research Projects

Research area

The main goal of the Department is to develop new, effective antiviral strategies against newly emerging pathogens, e.g. influenza virus, SARS-CoV-1, SARS-CoV-2, MERS-CoV. An effective method of fighting viruses requires extended basic research on the replication cycle of viruses and the interactions between the pathogen and the host cell, hence the main research topics of the Department include:

  • virus entry mechanism, including the proteolytic processing of viral surface protein;
  • virus – host cell interactions, i.e. interactions between the viral defective interfering particles and host cell proteins;
  • molecular diagnostic of infectious diseases.
Keywords:
  • Emerging viruses 
  • Transmembrane serine proteases type II
  • TMPRSS2
  • Proteolytic activation of surface viral protein ·
  • Hemagglutinin
  • Spike protein
  • Influenza virus
  • SARS-CoV-1, SARS-CoV-2, MERS-CoV
  • mRNA secondary structure
  • antisense oligonucleotide
  • new antiviral strategies
  • molecular diagnostic

Research activity

  • ‘TMPRSS2 – a potential new drug target and a determinant of COVID19 outcome’, National Science Centre ‘EXPRESS CALL TO FUND RESEARCH ON COVID-19’ . (UMO-2020/01/0/NZ6/00152)
  • ‘Molecular basics of type II transmembrane serine proteases (TTSPs)-mediated activation of influenza viruses’, National Science Centre ‘Beethoven Life 1 ’. (UMO-2018/31/F/NZ1/03891)
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